Acquired B antigens have been found in which group of individuals?

Acquired B antigens have been found in which group of individuals?

• A. Bombay individuals
• B. Group O persons
• C. All blood groups
• D. Group A persons

Answer: (D)

Acquired B antigens are typically the result of the presence of certain bacterial enzymes that modify the antigenic structure of the red blood cells. This phenomenon can occur in individuals with group A blood due to the addition of specific carbohydrate structures that resemble the B antigen. In these cases, the individual may test positive for the B antigen, despite being phenotypically type A. This acquisition of the B-like characteristics most commonly occurs in patients with infections or certain medical conditions that lead to the expression of these modified antigens. Consequently, group A individuals may exhibit acquired B antigenicity in their blood, particularly where their immune response or microbiome alters the terminal sugar residue of their antigenic determinants. While it's interesting to consider how other groups might also show variations in antigen expression due to different conditions, the presence of acquired B antigen specifically aligns with the biological and immunological mechanisms relevant to group A individuals.

Acquired B antigens are typically the result of the presence of certain bacterial enzymes that modify the antigenic structure of the red blood cells. This phenomenon can occur in individuals with group A blood due to the addition of specific carbohydrate structures that resemble the B antigen. In these cases, the individual may test positive for the B antigen, despite being phenotypically type A.

This acquisition of the B-like characteristics most commonly occurs in patients with infections or certain medical conditions that lead to the expression of these modified antigens. Consequently, group A individuals may exhibit acquired B antigenicity in their blood, particularly where their immune response or microbiome alters the terminal sugar residue of their antigenic determinants.

While it's interesting to consider how other groups might also show variations in antigen expression due to different conditions, the presence of acquired B antigen specifically aligns with the biological and immunological mechanisms relevant to group A individuals.