If a patient developed anti-C, anti-E, and anti-D antibodies, can compatible blood be found?

If a patient developed anti-C, anti-E, and anti-D antibodies, can compatible blood be found?

• A. It is almost impossible to find blood lacking C, E, and D antigens.
• B. rr blood could be used without causing a problem.
• C. R0R0 blood may be used as it lacks all three antigens.
• D. Although rare, r'r blood may come from close relatives.

Answer: (B)

The presence of anti-C, anti-E, and anti-D antibodies in a patient complicates the search for compatible blood because these antibodies can cause transfusion reactions if the donor blood contains the corresponding antigens. In this case, the option stating that rr blood could be used without causing a problem is correct because rr blood type, which has the genotype for the Rh system, specifically lacks the D antigen as well as the C and E antigens. Since the patient has antibodies against these antigens, transfusing blood from an rr donor would not pose a risk of an immune reaction, thus providing a safe transfusion option. The other options suggest situations where compatible blood would either be difficult to find or may still contain antigens that would react with the patient's antibodies. Consequently, the selection of donors must be very cautious to avoid exposing the patient to these antigens, making the identification of rr blood a prudent decision in this context.

The presence of anti-C, anti-E, and anti-D antibodies in a patient complicates the search for compatible blood because these antibodies can cause transfusion reactions if the donor blood contains the corresponding antigens.

In this case, the option stating that rr blood could be used without causing a problem is correct because rr blood type, which has the genotype for the Rh system, specifically lacks the D antigen as well as the C and E antigens. Since the patient has antibodies against these antigens, transfusing blood from an rr donor would not pose a risk of an immune reaction, thus providing a safe transfusion option.

The other options suggest situations where compatible blood would either be difficult to find or may still contain antigens that would react with the patient's antibodies. Consequently, the selection of donors must be very cautious to avoid exposing the patient to these antigens, making the identification of rr blood a prudent decision in this context.