If a unit of packed RBCs is split using an open system, what must be done with the second half unit?

If a unit of packed RBCs is split using an open system, what must be done with the second half unit?

• A. Must be issued within 24 hours
• B. Must be issued within 48 hours
• C. Must be irradiated
• D. Must retain the original expiration date

Answer: (A)

When a unit of packed red blood cells (RBCs) is split using an open system, the second half unit must be issued within 24 hours. This is due to the risk of bacterial contamination and loss of sterility associated with an open system. Once the unit is opened, it cannot maintain its full storage integrity as it becomes exposed to the environment. The 24-hour timeframe is a critical guideline to ensure that the transfusion remains safe and that the viability of the components is conserved as much as possible. Thus, timely issuance helps minimize the risk of adverse reactions in the recipient and supports effective blood management protocols. This guideline is part of the broader practice in blood banking that emphasizes safety in handling blood products, particularly when considering how the integrity of the blood product may be compromised after opening the original sterile packaging.

When a unit of packed red blood cells (RBCs) is split using an open system, the second half unit must be issued within 24 hours. This is due to the risk of bacterial contamination and loss of sterility associated with an open system. Once the unit is opened, it cannot maintain its full storage integrity as it becomes exposed to the environment.

The 24-hour timeframe is a critical guideline to ensure that the transfusion remains safe and that the viability of the components is conserved as much as possible. Thus, timely issuance helps minimize the risk of adverse reactions in the recipient and supports effective blood management protocols.

This guideline is part of the broader practice in blood banking that emphasizes safety in handling blood products, particularly when considering how the integrity of the blood product may be compromised after opening the original sterile packaging.