What is the expiration time for cryoprecipitate once pooled in an open system?

When cryoprecipitate is pooled in an open system, it must be used within a short time frame due to the risk of bacterial contamination. The expiration time for pooled cryoprecipitate in an open system is typically 4 hours. This stringent time limit ensures that it is used while still safe for patient administration, as the open system increases the exposure to potential microbial contaminants. This precaution is vital in blood banking and transfusion medicine to maintain patient safety and product integrity. Other time frames mentioned, such as 6, 8, or 24 hours, extend beyond safety guidelines and are not applicable for cryoprecipitate pooled in an open system.