What is the role of Rh immune globulin (RhIg) in pregnancy?

Prepare for the Harr Immunology, Serology and Blood Bank Test. Study with flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Rh immune globulin (RhIg) plays a critical role in preventing the sensitization of an Rh-negative mother to Rh-positive fetal red blood cells. During pregnancy or delivery, if there is any mixing of maternal and fetal blood, an Rh-negative mother can develop antibodies against Rh-positive red cells, which could lead to hemolytic disease of the newborn in subsequent pregnancies. RhIg is administered to Rh-negative mothers at certain times during pregnancy, such as around the 28th week and within 72 hours after delivery, to prevent the mother's immune system from recognizing and attacking Rh-positive cells. This proactive measure safeguards future pregnancies by ensuring that the mother does not become immunized against Rh-positive blood, thus protecting her potential Rh-positive babies from hemolytic disease.

The other options do not accurately describe the primary purpose of RhIg. It is not used to treat existing hemolytic disease; instead, it is a preventive measure. While it does support a safer pregnancy by preventing sensitization, it does not correct blood type discrepancies in the mother, nor does it facilitate delivery; its main focus is on preventing immunization against Rh-positive red cells.

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