What is the storage requirement for red cell units intended for transfusion?

Red cell units intended for transfusion must be stored refrigerated at a temperature range of 1°C to 6°C. This storage condition is critical because it preserves the viability of the red blood cells by slowing down metabolic processes and minimizing the risk of bacterial growth. At these temperatures, red blood cells can be stored for a certain period, typically up to 42 days, depending on the preservative used in the blood collection bag.

Storing red blood cells at room temperature can lead to rapid deterioration in quality and an increased risk of hemolysis and bacterial contamination. On the other hand, freezing red blood cells at temperatures around -15°C or colder is typically reserved for long-term storage of red cell units and requires specific preparation methods to ensure cell integrity upon thawing. Thermal insulated containers are used for transporting blood products but do not provide the continuous cryopreservation setting required for red cells prior to transfusion.

Thus, the appropriate storage method adheres to stringent guidelines to ensure patient safety and the effectiveness of the transfusion therapy.