What might account for the absence of Fya, Fyb, and Xga antigens in an individual?

Prepare for the Harr Immunology, Serology and Blood Bank Test. Study with flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Multiple Choice

What might account for the absence of Fya, Fyb, and Xga antigens in an individual?

Explanation:
The absence of Fya, Fyb, and Xga antigens in an individual is primarily influenced by genetic factors, which are closely tied to both race and gender. Specifically, the inheritance patterns of these antigens are linked to specific alleles that can vary between different populations as well as between males and females. In particular, the Fya and Fyb antigens belong to the Duffy blood group system, and their distribution can show significant geographic and ethnic variation. For instance, the frequency of the Fya and Fyb antigens can be significantly lower in certain populations, particularly among individuals of African descent, due to genetic differences. Similarly, the Xga antigen follows X-linked inheritance, which means that gender plays a role in its expression. Males have only one X chromosome, while females have two, which can affect the likelihood of expressing this antigen. By considering both gender and race, one can understand how these factors contribute to an individual’s antigen expression. Therefore, the choice indicating that both gender and race can account for the absence of these antigens provides a comprehensive explanation rooted in the genetic basis of blood group systems.

The absence of Fya, Fyb, and Xga antigens in an individual is primarily influenced by genetic factors, which are closely tied to both race and gender. Specifically, the inheritance patterns of these antigens are linked to specific alleles that can vary between different populations as well as between males and females.

In particular, the Fya and Fyb antigens belong to the Duffy blood group system, and their distribution can show significant geographic and ethnic variation. For instance, the frequency of the Fya and Fyb antigens can be significantly lower in certain populations, particularly among individuals of African descent, due to genetic differences. Similarly, the Xga antigen follows X-linked inheritance, which means that gender plays a role in its expression. Males have only one X chromosome, while females have two, which can affect the likelihood of expressing this antigen.

By considering both gender and race, one can understand how these factors contribute to an individual’s antigen expression. Therefore, the choice indicating that both gender and race can account for the absence of these antigens provides a comprehensive explanation rooted in the genetic basis of blood group systems.

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