What procedure should be taken for a patient with a prior history of anti-Jkb antibodies when ordering blood?

What procedure should be taken for a patient with a prior history of anti-Jkb antibodies when ordering blood?

• A. Antigen type units for the Jkb antigen and only crossmatch units positive for Jkb
• B. Antigen type units for the Jkb antigen and only crossmatch units negative for Jkb
• C. Randomly pull 4 units of blood that are ABO compatible and crossmatch
• D. Perform an immediate spin crossmatch on 4 Jkb-negative units

Answer: (B)

When a patient has a prior history of anti-Jkb antibodies, it is important to avoid any blood components that might contain the Jkb antigen to prevent an immunological reaction. Therefore, the appropriate procedure is to identify and select donor units that are negative for the Jkb antigen. By antigen typing the selected blood units for the Jkb antigen and only crossmatching units that test negative for Jkb, you can ensure that the blood products given to the patient do not trigger the production of antibodies or cause a transfusion reaction. This step is crucial because the patient's prior sensitization to the Jkb antigen means they could have an adverse reaction if they receive blood containing this specific antigen. The other procedures mentioned do not align with the necessary precautions for managing a patient with anti-Jkb antibodies. For instance, randomly selecting units without regard to the Jkb antigen or performing a crossmatch on units that might not be negative for Jkb could expose the patient to risk, contrary to established transfusion protocol for such cases.

When a patient has a prior history of anti-Jkb antibodies, it is important to avoid any blood components that might contain the Jkb antigen to prevent an immunological reaction. Therefore, the appropriate procedure is to identify and select donor units that are negative for the Jkb antigen.

By antigen typing the selected blood units for the Jkb antigen and only crossmatching units that test negative for Jkb, you can ensure that the blood products given to the patient do not trigger the production of antibodies or cause a transfusion reaction. This step is crucial because the patient's prior sensitization to the Jkb antigen means they could have an adverse reaction if they receive blood containing this specific antigen.

The other procedures mentioned do not align with the necessary precautions for managing a patient with anti-Jkb antibodies. For instance, randomly selecting units without regard to the Jkb antigen or performing a crossmatch on units that might not be negative for Jkb could expose the patient to risk, contrary to established transfusion protocol for such cases.