What testing is done for exchange transfusion when the mother's serum contains an alloantibody?

The correct choice involves performing ABO and Rh typing, an antibody screen, and a crossmatch prior to an exchange transfusion when the mother's serum contains an alloantibody.

In the context of exchange transfusion, it is crucial to ensure that the donor blood is compatible with the recipient's blood type. This helps prevent hemolytic reactions that could arise from the mother's alloantibodies reacting against antigens present on the transfused red blood cells. The ABO and Rh typing are essential to determine the blood group of both the donor and the recipient.

The antibody screen is performed to identify any alloantibodies that may be present in the mother’s serum and could potentially attack the transfused red cells. By knowing which antibodies are present, healthcare providers can select donor blood units that lack the corresponding antigens, minimizing the risk of a transfusion reaction.

Finally, the crossmatch is conducted to confirm the compatibility of the donor blood with the recipient's blood after considering both ABO, Rh, and any identified alloantibodies.

This comprehensive testing approach is vital to ensure safe and effective management of exchange transfusions in cases involving maternal alloantibodies, which greatly increases the likelihood of a successful transfusion outcome and reduces the risk of