What type of RBCs can be transfused to an A2 person with anti-A1?

An A2 individual has the A antigen on their red blood cells, but they may produce anti-A1 antibodies, which are directed against the A1 sub-type of A blood. Since anti-A1 reacts with A1 red blood cells but not with A2 cells, it is important to select a transfusion option that avoids this antibody's reactivity.

Blood type A red blood cells (specifically A1) would not be suitable for transfusion due to the presence of anti-A1, which would react against the A1 antigen. Type B blood does not have A antigens, so it is also considered incompatible with A2 individuals who produce anti-A1 antibodies. Transfusing AB type blood would also be inappropriate as it contains both A and B antigens.

Type O red blood cells, however, are universally compatible for transfusion as they do not have A or B antigens, making them an excellent choice for an A2 individual with anti-A1. This means transfusions can include both A2 and O type RBCs, as O does not provoke an immune response from the anti-A1 antibodies.

Thus, the best choice for transfusion would be O, along with the option of A2, provided the A2 cells