When can rejuvenated RBCs be transfused after preparation?

Rejuvenated red blood cells (RBCs) are those that have undergone a process to restore their viability and functionality after storage. This rejuvenation process typically involves the use of certain solutions and conditions that can help recover the metabolic capability of the stored cells, allowing for extended storage.

Once rejuvenated, these RBCs can be stored and transfused within a specified time frame to ensure their safety and efficacy. The correct timeframe for transfusing rejuvenated RBCs is within 24 hours after preparation. This is important because the rejuventation process must be carefully monitored to avoid the risks associated with extended storage, such as the potential for bacterial growth or deterioration of cell quality.

RBCs that are rejuvenated and held beyond this 24-hour window may lose their functionality and pose risks to patients. Therefore, the requirement to transfuse rejuvenated RBCs within 24 hours emphasizes the need to balance extended storage capabilities with patient safety during and post-transfusion.