Which blood products are indicated for a cancer patient with a hemoglobin of 8 g/dL and a severe infection?

For a cancer patient with a hemoglobin level of 8 g/dL and a severe infection, the use of irradiated red blood cells (RBCs), platelets, and granulocytes is the most appropriate choice.

In patients with cancer, particularly those undergoing chemotherapy or experiencing bone marrow suppression, there is a significant risk of transfusion-related complications due to the presence of donor lymphocytes that could lead to graft-versus-host disease (GVHD). This risk increases in immunocompromised individuals. Irradiating blood products helps to eliminate viable lymphocytes, thus preventing GVHD.

Additionally, the patient’s hemoglobin level of 8 g/dL suggests anemia that may necessitate red blood cell transfusion to improve oxygen transport and alleviate symptoms. The platelet transfusion is crucial as cancer treatment can lead to thrombocytopenia, and there is often a need to prevent bleeding, especially in the presence of severe infection where effective immune response and hemostasis are critical. Granulocyte transfusions can be particularly beneficial in managing severe infections, as they directly provide neutrophils to enhance the immune system's ability to fight off infection.

The combination of these products—irradiated RBCs, platelets, and granulocytes—addresses