Which devices may be used to deplete incompatible plasma from type O apheresis platelets to serve a transplant patient?

Which devices may be used to deplete incompatible plasma from type O apheresis platelets to serve a transplant patient?

• A. Cytospin/irradiator
• B. Water bath/centrifuge
• C. Centrifuge/sterile connecting device
• D. Cell washer/heat sealer

Answer: (C)

The correct choice is indeed based on the necessity of using devices that facilitate the effective removal of incompatible plasma from apheresis platelets. The use of a centrifuge is vital, as it allows for the separation of blood components based on density. When dealing with apheresis platelets, the centrifuge can effectively separate the platelet component from the plasma, ensuring that any incompatible plasma proteins or antibodies are minimized. In addition, a sterile connecting device plays an essential role in this process. It allows for the safe and sterile transfer of the separated platelets from one container to another without introducing contaminants, thereby maintaining the integrity of the platelet unit. This is particularly important in a clinical setting, especially for patients undergoing transplantation, who require the highest standards of sterility and compatibility to prevent complications. Devices like a cytospin or irradiator are not specifically designed for the separation or depletion of plasma from blood components but rather are used for other procedures, such as preparing cells for microscopic examination. Likewise, a water bath or heat sealer does not align with the goal of removing incompatible plasma in a sterile and efficient manner. Thus, the combination of a centrifuge and a sterile connecting device represents the most effective method for preparing type O apheresis platelets for

The correct choice is indeed based on the necessity of using devices that facilitate the effective removal of incompatible plasma from apheresis platelets. The use of a centrifuge is vital, as it allows for the separation of blood components based on density. When dealing with apheresis platelets, the centrifuge can effectively separate the platelet component from the plasma, ensuring that any incompatible plasma proteins or antibodies are minimized.

In addition, a sterile connecting device plays an essential role in this process. It allows for the safe and sterile transfer of the separated platelets from one container to another without introducing contaminants, thereby maintaining the integrity of the platelet unit. This is particularly important in a clinical setting, especially for patients undergoing transplantation, who require the highest standards of sterility and compatibility to prevent complications.

Devices like a cytospin or irradiator are not specifically designed for the separation or depletion of plasma from blood components but rather are used for other procedures, such as preparing cells for microscopic examination. Likewise, a water bath or heat sealer does not align with the goal of removing incompatible plasma in a sterile and efficient manner. Thus, the combination of a centrifuge and a sterile connecting device represents the most effective method for preparing type O apheresis platelets for