Which hepatitis B markers should be performed on blood products?

Which hepatitis B markers should be performed on blood products?

• A. HBsAg and anti-HBc
• B. Anti-HBs and anti-HBc
• C. HBeAg and HBcAg
• D. Anti-HBs and HBeAg

Answer: (A)

The selection of HBsAg and anti-HBc as the appropriate hepatitis B markers to be performed on blood products is based on the significance of these markers in assessing the presence of hepatitis B virus (HBV) infection and the potential risk of transmission through blood transfusions. HBsAg, or hepatitis B surface antigen, is the primary marker used for identifying active HBV infection. The presence of HBsAg indicates that an individual is currently infected and can transmit the virus. Testing for HBsAg in blood products is crucial because it helps to ensure that blood donations do not come from individuals who are actively infected with HBV. Anti-HBc, or antibody to hepatitis B core antigen, is an IgM or IgG antibody produced in response to HBV infection. The presence of anti-HBc indicates that an individual has been exposed to HBV, as it appears soon after the infection and typically persists for life. Testing for anti-HBc assists in identifying those who may have been infected in the past or are currently infected but may not be detected by HBsAg alone due to low viral titers or in cases of resolved infections. By testing for both HBsAg and anti-HBc, blood banks can effectively screen for both active infections and

The selection of HBsAg and anti-HBc as the appropriate hepatitis B markers to be performed on blood products is based on the significance of these markers in assessing the presence of hepatitis B virus (HBV) infection and the potential risk of transmission through blood transfusions.

HBsAg, or hepatitis B surface antigen, is the primary marker used for identifying active HBV infection. The presence of HBsAg indicates that an individual is currently infected and can transmit the virus. Testing for HBsAg in blood products is crucial because it helps to ensure that blood donations do not come from individuals who are actively infected with HBV.

Anti-HBc, or antibody to hepatitis B core antigen, is an IgM or IgG antibody produced in response to HBV infection. The presence of anti-HBc indicates that an individual has been exposed to HBV, as it appears soon after the infection and typically persists for life. Testing for anti-HBc assists in identifying those who may have been infected in the past or are currently infected but may not be detected by HBsAg alone due to low viral titers or in cases of resolved infections.

By testing for both HBsAg and anti-HBc, blood banks can effectively screen for both active infections and