Which serotype of HPV is primarily associated with cervical cancer?

Which serotype of HPV is primarily associated with cervical cancer?

• A. Low-risk serotype
• B. High-risk serotype
• C. Non-virulent serotype
• D. Oncogenic serotype

Answer: (B)

The choice identifying high-risk serotypes of HPV as being primarily associated with cervical cancer is grounded in established research linking specific strains of the virus to oncogenesis. High-risk serotypes, most notably HPV types 16 and 18, are known for their ability to integrate into the host genome and disrupt normal cell cycle regulation, leading to malignant transformation of cervical epithelial cells. These high-risk serotypes have been directly implicated in the majority of cervical cancer cases, making them a significant focus in cervical cancer screening and prevention strategies. In contrast to high-risk serotypes, low-risk serotypes are more commonly associated with benign conditions, such as genital warts, and do not lead to cancer. Non-virulent serotypes do not cause infection or disease, while oncogenic serotype is another term that could also refer to high-risk serotypes; however, in the context of public health education and prevention strategies, the clear identification of high-risk serotypes provides more effective guidance on managing cervical cancer risk.

The choice identifying high-risk serotypes of HPV as being primarily associated with cervical cancer is grounded in established research linking specific strains of the virus to oncogenesis. High-risk serotypes, most notably HPV types 16 and 18, are known for their ability to integrate into the host genome and disrupt normal cell cycle regulation, leading to malignant transformation of cervical epithelial cells.

These high-risk serotypes have been directly implicated in the majority of cervical cancer cases, making them a significant focus in cervical cancer screening and prevention strategies. In contrast to high-risk serotypes, low-risk serotypes are more commonly associated with benign conditions, such as genital warts, and do not lead to cancer. Non-virulent serotypes do not cause infection or disease, while oncogenic serotype is another term that could also refer to high-risk serotypes; however, in the context of public health education and prevention strategies, the clear identification of high-risk serotypes provides more effective guidance on managing cervical cancer risk.